Tool
PT-141 dosage calculator
A reconstitution calculator preloaded with the FDA-approved Vyleesi (bremelanotide) label dose, 1.75 mg, converted to micrograms. Enter your own vial mass, diluent, and dose to get concentration, draw volume, and insulin-syringe units. Arithmetic only - it does not tell you what dose to use.
See also:PT-141 dosage: the approved label·PT-141 main guide
Your vial
Printed on the vial. There is no standard size - enter what yours says.
This changes how much you draw - never how many doses the vial holds.
100 units per mL. 1 unit = 0.01 mL. This is what almost every insulin syringe sold is, in every barrel size.
Capacity only. A 1 mL U-100 syringe holds 100 units - the scale decides that, not the barrel.
Draw this much
= 0.35 mL on a 1 mL U-100 syringe
- Concentration
- 5,000 mcg/mL
- Exact volume
- 0.35 mL
- Dose you actually get
- 1,750 mcg
- Doses per vial(unaffected by water volume)
- 5
Results update in the address bar, so you can copy the link to save or share a calculation. Nothing is stored, and there is no account.
What PT-141 dosing actually looks like
The only regulator-established dose of PT-141 (bremelanotide) is the Vyleesi label: 1.75 mg by subcutaneous injection, at least 45 minutes before sexual activity, capped at once every 24 hours and eight times a month. That figure came from a dose-ranging trial in premenopausal women. A separate, older trial in men used a different route and a much larger amount - 10 mg intranasal - which never became an approved regimen. Read the full breakdown, including the label table and both trials, on thePT-141 dosage page.
Common questions
What is the FDA-approved PT-141 (bremelanotide) dose?
1.75 mg, injected subcutaneously, at least 45 minutes before anticipated sexual activity, no more than once in 24 hours and no more than eight times a month. That is the Vyleesi label dose for premenopausal women with acquired, generalised hypoactive sexual desire disorder - see the PT-141 dosage page for the full label table.
Why does the calculator start at 1,750 mcg?
1.75 mg equals 1,750 mcg. This tool preloads the FDA-approved Vyleesi label dose, converted to micrograms, as its starting figure - not a dose for a research-labelled vial, which has no verified concentration.
Does Vyleesi come as a vial I reconstitute?
No. Vyleesi is a pre-filled, single-dose autoinjector - there is nothing to reconstitute. The vial and diluent fields below apply only if you are working out arithmetic for a research-sold PT-141 vial, which is a different, unapproved product with no confirmed concentration.
Is PT-141 taken daily?
No. The approved Vyleesi regimen is as needed before activity, capped at once every 24 hours and eight times a month - not a daily injection and not a cycle.
Where does the 10 mg figure some sources mention come from?
An older trial in men tested bremelanotide as a 10 mg intranasal spray - a different route and a much larger amount than the approved 1.75 mg subcutaneous dose. It did not lead to an approval and is not the regimen used today. See the PT-141 dosage page for the full comparison.