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Research peptides

Vilon: What It Is, Dosage and What the Evidence Shows

Vilon is a Khavinson-group dipeptide sold for immune support. Real cell-culture studies exist under its own name - still no human trial.

The short version

Vilon is a synthetic two-amino-acid peptide (Lys-Glu) from the Khavinson short-peptide bioregulator programme, sold as a thymus and immune-system bioregulator. Unlike some others in its family, it has real cell-culture studies under its own name, in thymus and immune cells. No human trial of any kind has been published.

  • Vilon has real, checkable cell-culture studies under its own name, in thymus and immune cells, matching what it is marketed for.
  • No published human trial exists at any dose, for any use.
  • Dosing guides commonly describe roughly 10-20 mg by mouth once a day, in 20-30 day courses. That is not trial-established.
  • Sources on an injectable form disagree by roughly a thousandfold on dose, so this page does not report one.

Vilon at a glance

What it is
Synthetic dipeptide (Lys-Glu), one of the Khavinson-group short peptide bioregulators
Main use
Marketed as a thymus and immune-system bioregulator, sold for immune support and healthy ageing.
Also called
KE peptide, Lys-Glu dipeptide
Molecular formula
C11H21N3O5 (275.30 g/mol) Structure
Evidence
Animal / lab only
US status
Research use only
Half-life
Not established in humans
How it is taken
By mouth
Common protocol
10-20 mg, once daily by mouth, for 2.9-4.3 weeks (common practice, not trial-established)

Vilon is one of the Khavinson-group peptide bioregulators, sold as a thymus and immune-system bioregulator. Of the three I covered together (Vilon, Cartalax and Testagen), Vilon’s evidence matches its marketing most closely. Even so, that evidence is cell culture, not a human trial.

What is Vilon?

Vilon is a synthetic dipeptide of two amino acids, Lys-Glu (lysine-glutamic acid). It comes from the St Petersburg peptide-bioregulator programme described on the bioregulator hub page. It was first described from thymus tissue and is marketed for immune support and healthy ageing.

Animal / lab only

Studied in cells or animals. No controlled trials in humans. Vilon has real, checkable evidence under its own name, unlike Cartalax or Testagen. One study names it among five Khavinson-group peptides tested on human THP-1 monocyte/macrophage cells. A second, about 'Vilon and its analogue', tested dipeptides in cultured human and animal thymus cells. Both are cell-culture experiments, not animal or human trials, and both come from the same small Russian research tradition.

Vilon structure

2D chemical structure of Vilon, C11H21N3O5
2D structure from PubChem CID 7010502 (NCBI, public domain). Open it in PubChem to zoom or view in 3D.
Molecular formula
C11H21N3O5
Molecular weight
275.30 g/mol
Length
2 amino acids
Sequence
KE
Modifications
L-Lys-L-Glu; free N- and C-termini.
PubChem CID
7010502

Identity checked against FDA Global Substance Registration System (UNII H34V7IM5ML).

How Vilon works

The wider bioregulator theory proposes that short peptides like this one act on genes involved in how immune cells mature (differentiation); the bioregulator hub page covers it. For Vilon this is more than theory: the cell-culture studies below test exactly that kind of outcome, in thymus and monocyte cells.

Vilon benefits: what the research shows

Two cell-culture studies name Vilon:

Vilon dosage

Dosing guides most often describe an oral course of roughly 10-20 mg once a day, for 20-30 days, on an empty stomach and repeated every 3-6 months. That is common practice, not a dose any trial or regulator has set.

Sources describing an injectable (subcutaneous) version disagree by roughly a thousandfold: the figures I found ran from about 10 mcg to 10 mg a day for the same compound. So this page gives no dose for that route.

Common protocol

What is commonly used, not a dose established in trials. No regulator has set a dose for Vilon.

Dose
10-20 mg
How often
once daily by mouth
Route
By mouth
Cycle length
2.9-4.3 weeks
Break between cycles
13-26 weeks
Timing
On an empty stomach; both sources describing this route say to take it before eating.

Sources describing an injectable (subcutaneous) form of Vilon exist, but the doses they state for that route range from about 10 mcg to 10 mg per day - a roughly thousandfold spread with no two sites agreeing - so this record reports only the oral capsule course, where two sources agree reasonably well.

Plan a cycle in the protocol builder

What is not established

  • No published human trial exists for Vilon, at any dose, for any use.
  • The cell studies don’t give a human dose. They used a lab concentration in a dish, not a milligram amount for a person.
  • No dose has been shown safe or effective for any use, by any regulator.
  • Sources disagree sharply on the injectable dose, by roughly a thousandfold, so only the oral course, where two sources broadly agree, is given above.

Vilon side effects

No human safety study exists for Vilon at any dose, so there is no verified side-effect rate.

It is sold as a research chemical or unregulated capsule or vial product, so no regulator checks that a batch matches its label for contents, purity or even the peptide’s identity. Because an injectable form is also sold, see peptide injection-site reactions for the general risks of injecting under the skin, which are not specific to this compound.

US legal status - Research use only

Sold for laboratory research use only. Not approved by the FDA for human use, and cannot be lawfully marketed as a supplement or a medicine. Products sold this way are not made to pharmaceutical quality standards, and their contents are not verified by anyone.

Vilon is not approved for human use by the FDA or any regulator I can verify. It is sold internationally as a research chemical or an unregulated capsule or vial product, outside any approved drug supply chain.

Regulatory changes for this compound and others, as they happen: US peptide regulation tracker.

How Vilon compares

Bioregulators. Doses for unapproved compounds are common practice, not trial-established. All bioregulators peptides →

CompoundMain useEvidenceUsual doseUS status
VilonMarketed as a thymus and immune-system bioregulator, sold for immune support and healthy ageing.Animal / lab only10-20 mg, once daily by mouthResearch use only
EpitalonSold for longevity and anti-aging on the basis of telomere research.Animal / lab only5-10 mg, once nightly, every night, for the length of the cycleResearch use only
PinealonSold for cognition, focus and healthy aging.Limited human data1-2 mg, once daily, morning preferred; some protocols run 5 days a week rather than every dayResearch use only
CartalaxMarketed for cartilage and joint support, sold as a "cartilage bioregulator" for age-related joint wear.Animal / lab only200 mcg, once dailyResearch use only
TestagenMarketed for testosterone and reproductive-system support, sold as a "testes bioregulator."Animal / lab only10-20 mg, once daily by mouthResearch use only
VesugenMarketed as a vascular-tissue bioregulator for cardiovascular and blood-vessel aging; more recent papers from the same research group also study it as a candidate for age-related cognitive decline.Limited human data500-5000 mcg, once daily, subcutaneous, commonly started low and titrated upward over the first 1-3 weeksResearch use only
CardiogenMarketed as a heart-tissue bioregulator for cardiovascular aging, from the Khavinson organ-specific peptide programme.Animal / lab only200-2000 mcg, once daily, subcutaneous, most commonly cited around 1 mg/dayResearch use only
ProstamaxMarketed as a prostate-tissue bioregulator for age-related prostate change, from the Khavinson organ-specific peptide programme.Animal / lab only750-2000 mcg, once daily, subcutaneous, often started lower and increased after 1-4 weeksResearch use only

Where to buy Vilon for research

Each vendor is checked against my vendor checklist.

  1. 1.BioEdge Research Labs

    20 mg vial

    • No FDA warning letter found
    • Names its testing lab
    • Batch COAs published

See all vendors and how they compare →

Common questions

Is there any published research on Vilon specifically?

Yes, unlike some others in this family. One study names Vilon among five Khavinson-group peptides tested on human immune cells. A second, about "Vilon and its analogue", tested it in cultured human and animal thymus cells. Both are cell-culture experiments, not animal or human trials.

What is the usual Vilon dose?

Dosing guides most often describe roughly 10-20 mg by mouth once a day for 20-30 days, repeated every 3-6 months. That is common practice, not a dose any trial or regulator has set. Sources on an injectable version disagree by roughly a thousandfold, so this page gives no injectable figure.

What are the side effects of Vilon?

No human safety study exists at any dose, so there is no verified side-effect rate. See the side effects section for what is and isn't known.

References (2 sources)

Bibliographic detail is fetched from PubMed, not written by me - so a citation here cannot drift from the paper it names. Study design comes from PubMed's own tags rather than my judgement.

  1. 1.Avolio F, Martinotti S, Khavinson VK et al. Peptides Regulating Proliferative Activity and Inflammatory Pathways in the Monocyte/Macrophage THP-1 Cell Line. Int J Mol Sci. 2022;23(7).StudyPMID 35408963full text
  2. 2.Sevostianova NN, Linkova NS, Polyakova VO et al. Immunomodulating effects of Vilon and its analogue in the culture of human and animal thymus cells. Bull Exp Biol Med. 2013;154(4):562-5.StudyPMID 23486604